Abstract
Background:
- The acid phosphatase 1 (ACP1) gene encodes low molecular weight protein tyrosine phosphatase (LMPTP), which is overexpressed in PCa.
- Previous studies demonstrate that LMPTP plays a critical role in PCa growth and metastasis and is evolving as a potential therapeutic target.
- Thus, we analyzedACP1expression in primary and metastatic PCa samples and the association ofACP1with molecular profiles and clinical outcomes.